Enzyme

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EC Tree
     2. Transferases
        2.6 Transferring nitrogenous groups
            2.6.99 Transferring other nitrogenous groups
ID:2.6.99.3
Description:O-ureido-L-serine synthase.
Cath: 3.40.50.1100;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.99.3
BRENDA Enzyme Link: BRENDA 2.6.99.3
KEGG Enzyme Link: KEGG2.6.99.3
BioCyc Enzyme Link: BioCyc 2.6.99.3
ExPASy Enzyme Link: ExPASy2.6.99.3
EC2PDB Enzyme Link: EC2PDB 2.6.99.3
ExplorEnz Enzyme Link: ExplorEnz 2.6.99.3
PRIAM enzyme-specific profiles Link: PRIAM 2.6.99.3
IntEnz Enzyme Link: IntEnz 2.6.99.3
MEDLINE Enzyme Link: MEDLINE 2.6.99.3
MSA:

2.6.99.3;

Phylogenetic Tree:

2.6.99.3;

Uniprot:
M-CSA:
RHEA:36263 hydroxyurea + O-acetyl-L-serine = acetate + H(+) + O-ureido-L-serine
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[OH;+0:6]>>[*:5]-[O;H0;+0:6]-[CH2;+0:2]-[*:1].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway.Uda N, Matoba Y, Kumagai T, Oda K, Noda M, Sugiyama M2013 Jun23529730
Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M2010 Mar20086163