EC number:2.7.1.1
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
3D structure
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| PDB |
1BG3;
4FPB;
4FPA;
4FOI;
4FOE;
4F9O;
1QHA;
1HKB;
1HKC;
1DGK;
1CZA;
1BDG;
2YHX;
1IG8;
5V4X;
5V4W;
4RCH;
4NO7;
4MLH;
4MLE;
4LC9;
4L3Q;
4IXC;
4IWV;
4ISG;
4ISF;
4ISE;
4DHY;
4DCH;
3VF6;
3VEY;
3VEV;
3S41;
3QIC;
3IMX;
3IDH;
3ID8;
3H1V;
3GOI;
3FR0;
3FGU;
3F9M;
3A0I;
1V4T;
1V4S;
5ZQT;
5HG1;
5HFU;
5HEX;
4QS9;
4QS8;
4QS7;
4JAX;
3O8M;
3O80;
3O6W;
3O5B;
3O4W;
3O1W;
3O1B;
3O08;
3HM8;
3B8A;
2NZT;
1HKG;
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References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.1 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.1 |
| KEGG Enzyme Link: | KEGG2.7.1.1 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.1 |
| ExPASy Enzyme Link: | ExPASy2.7.1.1 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.1 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.1 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.1 |
| RHEA:10948 | ATP + D-glucosamine = ADP + D-glucosamine 6-phosphate + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Hexokinases of Schistosoma mansoni. | BUEDING E, MACKINNON JA | 1955 Aug | 13242546 |
| Isolation of a glucosamine-specific kinase, a unique enzyme of Vibrio cholerae. | Park JK, Wang LX, Roseman S | 2002 May 3 | 11850417 |
| RHEA:11028 | ATP + D-mannose = ADP + D-mannose 6-phosphate + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of the mannokinase from Escherichia coli. | Sebastian J, Asensio C | 1972 Jul | 4557975 |
| Hexokinases of Schistosoma mansoni. | BUEDING E, MACKINNON JA | 1955 Aug | 13242546 |
| The glucomannokinase of Prevotella bryantii B(1)4 and its potential role in regulating beta-glucanase expression. | Fields MW, Russell JB | 2001 Apr | 11283299 |
| RHEA:16125 | ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| RHEA:17825 | ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mammalian glucokinase and its gene. | Iynedjian PB | 1993 Jul 1 | 8392329 |
| Purification and kinetic characterization of a specific glucokinase from Streptococcus mutans OMZ70 cells. | Porter EV, Chassy BM, Holmlund CE | 1982 Dec 20 | 7150605 |
| Glucokinase of Dictyostelium discoideum. | Baumann P | 1969 Dec | 4312464 |
| Molecular and cellular regulation of human glucokinase. | Sternisha SM, Miller BG | 2019 Mar 15 | 30641049 |
| Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations. | Heredia VV, Carlson TJ, Garcia E, Sun S | 2006 Dec 29 | 17082186 |
| RHEA:22740 | ATP + D-hexose = ADP + D-hexose 6-phosphate + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Arabidopsis thaliana hexokinase cDNA isolated by complementation of yeast cells. | Dai N, Schaffer AA, Petreikov M, Granot D | 1995 Jun | 7610198 |
| Fructose is a good substrate for rat liver 'glucokinase' (hexokinase D). | Cárdenas ML, Rabajille E, Niemeyer H | 1984 Sep 1 | 6477520 |