EC number:2.7.1.107

Enzyme

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EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.107
Description:Diacylglycerol kinase (ATP).
Alternative Name: Diglyceride kinase.
DGK.
Prosite: PDOC50146; PDOC00820;
PDB:
PDBScop
5DWK
5D6I
5D57
5D56
4UYO
 » show all
Cath: 1.10.150.50; 1.10.238.110; 1.10.287.3610; 1.10.3830.10; 3.30.60.20; 3.40.50.10330; 2.60.200.40;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.107
BRENDA Enzyme Link: BRENDA 2.7.1.107
KEGG Enzyme Link: KEGG2.7.1.107
BioCyc Enzyme Link: BioCyc 2.7.1.107
ExPASy Enzyme Link: ExPASy2.7.1.107
EC2PDB Enzyme Link: EC2PDB 2.7.1.107
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.107
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.107
IntEnz Enzyme Link: IntEnz 2.7.1.107
MEDLINE Enzyme Link: MEDLINE 2.7.1.107

EC number:2.7.1.107

MSA:

2.7.1.107;
Phylogenetic Tree:

2.7.1.107;
Uniprot:
M-CSA:
RHEA:10272 a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells.Bektas M, Payne SG, Liu H, Goparaju S, Milstien S, Spiegel S2005 Jun 615939762