Enzyme

Download
EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.114
Description:AMP--thymidine kinase.
Alternative Name: Adenylate-nucleoside phosphotransferase.
Cath: 3.30.60.20; 3.40.50.300;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.114
BRENDA Enzyme Link: BRENDA 2.7.1.114
KEGG Enzyme Link: KEGG2.7.1.114
BioCyc Enzyme Link: BioCyc 2.7.1.114
ExPASy Enzyme Link: ExPASy2.7.1.114
EC2PDB Enzyme Link: EC2PDB 2.7.1.114
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.114
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.114
IntEnz Enzyme Link: IntEnz 2.7.1.114
MEDLINE Enzyme Link: MEDLINE 2.7.1.114
MSA:

2.7.1.114;

Phylogenetic Tree:

2.7.1.114;

Uniprot:
M-CSA:
RHEA:14913 AMP + thymidine = adenosine + dTMP
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel herpes simplex virus-induced enzyme.Falke D, Nehrbass W, Brauer D, Müller WE1981 Apr6267178
Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase.Falke D, Labenz J, Brauer D, Müller WE1982 Oct 206293576