| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.114 |
|---|---|
| Description: | AMP--thymidine kinase. |
| Alternative Name: |
Adenylate-nucleoside phosphotransferase. |
| Cath: | 3.30.60.20; 3.40.50.300; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.7.1.114 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.114 |
| KEGG Enzyme Link: | KEGG2.7.1.114 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.114 |
| ExPASy Enzyme Link: | ExPASy2.7.1.114 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.114 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.114 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.114 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.114 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.114 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:14913 | AMP + thymidine = adenosine + dTMP |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel herpes simplex virus-induced enzyme. | Falke D, Nehrbass W, Brauer D, Müller WE | 1981 Apr | 6267178 |
| Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase. | Falke D, Labenz J, Brauer D, Müller WE | 1982 Oct 20 | 6293576 |