EC number:2.7.1.140

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.140
Description:Inositol-tetrakisphosphate 5-kinase.
Alternative Name: 1D-myo-inositol-tetrakisphosphate 5-kinase.
Cath: 1.10.510.50; 3.30.1490.220; 3.30.470.10; 3.30.470.100; 3.30.470.20; 3.40.50.10820; 3.40.50.11370;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.140
BRENDA Enzyme Link: BRENDA 2.7.1.140
KEGG Enzyme Link: KEGG2.7.1.140
BioCyc Enzyme Link: BioCyc 2.7.1.140
ExPASy Enzyme Link: ExPASy2.7.1.140
EC2PDB Enzyme Link: EC2PDB 2.7.1.140
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.140
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.140
IntEnz Enzyme Link: IntEnz 2.7.1.140
MEDLINE Enzyme Link: MEDLINE 2.7.1.140

EC number:2.7.1.140

MSA:

2.7.1.140;
Phylogenetic Tree:

2.7.1.140;
Uniprot:
M-CSA:
RHEA:12717 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase, myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol 1,3,4,6-tetrakisphosphate 5-kinase.Shears SB1989 Nov 252584198
Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases.Stevenson-Paulik J, Odom AR, York JD2002 Nov 812226109