EC number:2.7.1.156
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.156 |
|---|---|
| Description: | Adenosylcobinamide kinase. |
| Alternative Name: |
AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. guanylyltransferase. Adenosylcobinamide kinase/adenosylcobinamide-phosphate |
| Cath: | 3.90.550.10; 3.40.50.300; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.156 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.156 |
| KEGG Enzyme Link: | KEGG2.7.1.156 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.156 |
| ExPASy Enzyme Link: | ExPASy2.7.1.156 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.156 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.156 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.156 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.156 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.156 |
EC number:2.7.1.156
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15769 | adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:1]-[O;H0;+0:2]-[P;H0;+0:4](=[*:3])(-[*:5])-[*:6].[*:8]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,. | Thompson TB, Thomas MG, Escalante-Semerena JC, Rayment I | 1998 May 26 | 9601028 |
| Purification and characterization of the bifunctional CobU enzyme of Salmonella typhimurium LT2. Evidence for a CobU-GMP intermediate. | O'Toole GA, Escalante-Semerena JC | 1995 Oct 6 | 7559521 |
| Analysis of the adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase (CobU) enzyme of Salmonella typhimurium LT2. Identification of residue His-46 as the site of guanylylation. | Thomas MG, Thompson TB, Rayment I, Escalante-Semerena JC | 2000 Sep 8 | 10869342 |
| Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site. | Thompson TB, Thomas MG, Escalante-Semerena JC, Rayment I | 1999 Oct 5 | 10529169 |
| RHEA:15765 | adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[O;H0;+0:8]-[*:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,. | Thompson TB, Thomas MG, Escalante-Semerena JC, Rayment I | 1998 May 26 | 9601028 |
| Purification and characterization of the bifunctional CobU enzyme of Salmonella typhimurium LT2. Evidence for a CobU-GMP intermediate. | O'Toole GA, Escalante-Semerena JC | 1995 Oct 6 | 7559521 |
| Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site. | Thompson TB, Thomas MG, Escalante-Semerena JC, Rayment I | 1999 Oct 5 | 10529169 |