EC number:2.7.1.162

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.162
Description:N-acetylhexosamine 1-kinase.
Alternative Name: N-acetylgalactosamine/N-acetylglucosamine 1-kinase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.162
BRENDA Enzyme Link: BRENDA 2.7.1.162
KEGG Enzyme Link: KEGG2.7.1.162
BioCyc Enzyme Link: BioCyc 2.7.1.162
ExPASy Enzyme Link: ExPASy2.7.1.162
EC2PDB Enzyme Link: EC2PDB 2.7.1.162
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.162
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.162
IntEnz Enzyme Link: IntEnz 2.7.1.162
MEDLINE Enzyme Link: MEDLINE 2.7.1.162

EC number:2.7.1.162

MSA:

2.7.1.162;
Phylogenetic Tree:

2.7.1.162;
Uniprot:
M-CSA:
RHEA:53724 ATP + N-acetyl-D-glucosamine = ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A cell wall recycling shortcut that bypasses peptidoglycan de novo biosynthesis.Gisin J, Schneider A, Nägele B, Borisova M, Mayer C2013 Aug23831760
RHEA:25428 ATP + N-acetyl-D-hexosamine = ADP + H(+) + N-acetyl-alpha-D-hexosamine 1-phosphate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Substrate specificity of N-acetylhexosamine kinase towards N-acetylgalactosamine derivatives.Cai L, Guan W, Wang W, Zhao W, Kitaoka M, Shen J, O'Neil C, Wang PG2009 Sep 1519683921
A chemoenzymatic route to N-acetylglucosamine-1-phosphate analogues: substrate specificity investigations of N-acetylhexosamine 1-kinase.Cai L, Guan W, Kitaoka M, Shen J, Xia C, Chen W, Wang PG2009 May 2819436918
Identification of N-acetylhexosamine 1-kinase in the complete lacto-N-biose I/galacto-N-biose metabolic pathway in Bifidobacterium longum.Nishimoto M, Kitaoka M2007 Oct17720833