EC number:2.7.1.163

Enzyme

Download
EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.163
Description:Hygromycin B 4-O-kinase.
Alternative Name: Hygromycin-B kinase.
Cath: 3.30.200.150; 3.90.1200.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.163
BRENDA Enzyme Link: BRENDA 2.7.1.163
KEGG Enzyme Link: KEGG2.7.1.163
BioCyc Enzyme Link: BioCyc 2.7.1.163
ExPASy Enzyme Link: ExPASy2.7.1.163
EC2PDB Enzyme Link: EC2PDB 2.7.1.163
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.163
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.163
IntEnz Enzyme Link: IntEnz 2.7.1.163
MEDLINE Enzyme Link: MEDLINE 2.7.1.163

EC number:2.7.1.163

MSA:

2.7.1.163;
Phylogenetic Tree:

2.7.1.163;
Uniprot:
M-CSA:
RHEA:26064 ATP + hygromycin B = 4-O-phosphohygromycin B + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:1]-[O;H0;+0:2]-[P;H0;+0:4](=[*:3])(-[*:5])-[*:6].[*:8]-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli.Rao RN, Allen NE, Hobbs JN Jr, Alborn WE Jr, Kirst HA, Paschal JW1983 Nov6318654