EC number:2.7.1.166

Enzyme

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EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.166
Description:3-deoxy-D-manno-octulosonic acid kinase.
Alternative Name: Kdo kinase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.166
BRENDA Enzyme Link: BRENDA 2.7.1.166
KEGG Enzyme Link: KEGG2.7.1.166
BioCyc Enzyme Link: BioCyc 2.7.1.166
ExPASy Enzyme Link: ExPASy2.7.1.166
EC2PDB Enzyme Link: EC2PDB 2.7.1.166
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.166
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.166
IntEnz Enzyme Link: IntEnz 2.7.1.166
MEDLINE Enzyme Link: MEDLINE 2.7.1.166

EC number:2.7.1.166

MSA:

2.7.1.166;
Phylogenetic Tree:

2.7.1.166;
Uniprot:
M-CSA:
RHEA:28506 alpha-Kdo-(2->6)-lipid IVA + ATP = 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:1]-[O;H0;+0:2]-[P;H0;+0:4](=[*:3])(-[*:5])-[*:6].[*:8]-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli.Brabetz W, Müller-Loennies S, Brade H2000 Nov 1010952982
A Haemophilus influenzae gene that encodes a membrane bound 3-deoxy-D-manno-octulosonic acid (Kdo) kinase. Possible involvement of kdo phosphorylation in bacterial virulence.White KA, Lin S, Cotter RJ, Raetz CR1999 Oct 2910531340