EC number:2.7.1.174

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.174
Description:Diacylglycerol kinase (CTP).
Alternative Name: Diglyceride kinase.
Diacylglycerol kinase (CTP dependent).
DAG kinase.
CTP-dependent diacylglycerol kinase.
Cath: 1.10.150.50; 1.10.238.110; 1.10.287.3610; 1.10.3830.10; 3.30.60.20; 3.40.50.10330; 2.60.200.40;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.174
BRENDA Enzyme Link: BRENDA 2.7.1.174
KEGG Enzyme Link: KEGG2.7.1.174
BioCyc Enzyme Link: BioCyc 2.7.1.174
ExPASy Enzyme Link: ExPASy2.7.1.174
EC2PDB Enzyme Link: EC2PDB 2.7.1.174
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.174
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.174
IntEnz Enzyme Link: IntEnz 2.7.1.174
MEDLINE Enzyme Link: MEDLINE 2.7.1.174

EC number:2.7.1.174

MSA:

2.7.1.174;
Phylogenetic Tree:

2.7.1.174;
Uniprot:
M-CSA:
RHEA:25948 a 1,2-diacyl-sn-glycerol + CTP = a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[O;H0;+0:8]-[*:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.Han GS, O'Hara L, Siniossoglou S, Carman GM2008 Jul 1818458076
An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth.Han GS, O'Hara L, Carman GM, Siniossoglou S2008 Jul 1818458075