EC number:2.7.1.181
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.181 |
|---|---|
| Description: | Polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol kinase. |
| Cath: | 1.10.510.10; 3.30.200.20; 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.181 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.181 |
| KEGG Enzyme Link: | KEGG2.7.1.181 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.181 |
| ExPASy Enzyme Link: | ExPASy2.7.1.181 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.181 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.181 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.181 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.181 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.181 |
EC number:2.7.1.181
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:40371 | alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-di-trans,octa-cis-undecaprenol + ATP = 3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-di-trans,octa-cis-undecaprenol + ADP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:1]-[O;H0;+0:2]-[P;H0;+0:4](=[*:3])(-[*:5])-[*:6].[*:8]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| In vitro reconstruction of the chain termination reaction in biosynthesis of the Escherichia coli O9a O-polysaccharide: the chain-length regulator, WbdD, catalyzes the addition of methyl phosphate to the non-reducing terminus of the growing glycan. | Clarke BR, Richards MR, Greenfield LK, Hou D, Lowary TL, Whitfield C | 2011 Dec 2 | 21990359 |
| Coordination of polymerization, chain termination, and export in assembly of the Escherichia coli lipopolysaccharide O9a antigen in an ATP-binding cassette transporter-dependent pathway. | Clarke BR, Greenfield LK, Bouwman C, Whitfield C | 2009 Oct 30 | 19734145 |
| Nonreducing terminal modifications determine the chain length of polymannose O antigens of Escherichia coli and couple chain termination to polymer export via an ATP-binding cassette transporter. | Clarke BR, Cuthbertson L, Whitfield C | 2004 Aug 20 | 15184370 |