EC number:2.7.1.189
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.189 |
|---|---|
| Description: | Autoinducer-2 kinase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.189 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.189 |
| KEGG Enzyme Link: | KEGG2.7.1.189 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.189 |
| ExPASy Enzyme Link: | ExPASy2.7.1.189 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.189 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.189 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.189 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.189 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.189 |
EC number:2.7.1.189
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15377 | (S)-4,5-dihydroxypentane-2,3-dione + ATP = (S)-4-hydroxy-2,3-pentanedione-5-phosphate + ADP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation. | Zhu J, Hixon MS, Globisch D, Kaufmann GF, Janda KD | 2013 May 29 | 23672516 |
| Cross species quorum quenching using a native AI-2 processing enzyme. | Roy V, Fernandes R, Tsao CY, Bentley WE | 2010 Feb 19 | 20025244 |
| Phosphorylation and processing of the quorum-sensing molecule autoinducer-2 in enteric bacteria. | Xavier KB, Miller ST, Lu W, Kim JH, Rabinowitz J, Pelczer I, Semmelhack MF, Bassler BL | 2007 Feb 20 | 17274596 |