EC number:2.7.1.191
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.191 |
|---|---|
| Description: | Protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. |
| Alternative Name: |
Mannose PTS permease. |
| Prosite: | PDOC00795; |
| PDB: |
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| Cath: | 3.30.1340.10; 3.30.1360.60; 3.40.50.510; 3.40.930.10; 1.20.58.280; 3.40.35.10; 3.40.50.2300; 2.70.70.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.191 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.191 |
| KEGG Enzyme Link: | KEGG2.7.1.191 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.191 |
| ExPASy Enzyme Link: | ExPASy2.7.1.191 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.191 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.191 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.191 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.191 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.191 |
EC number:2.7.1.191
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:49232 | D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein] |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[n;H0;+0:7]1:[*:8]:[n;H0;+0:9]:[*:10]:[*:11]:1>>[*:8]1:[n;H0;+0:7]:[*:11]:[*:10]:[nH;+0:9]:1.[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Membrane topology of the mannose transporter of Escherichia coli K12. | Huber F, Erni B | 1996 Aug 1 | 8774730 |
| The mannose transporter of Escherichia coli. Structure and function of the IIABMan subunit. | Stolz B, Huber M, Marković-Housley Z, Erni B | 1993 Dec 25 | 8262947 |
| The mannose transporter of Escherichia coli K12: oligomeric structure, and function of two conserved cysteines. | Rhiel E, Flükiger K, Wehrli C, Erni B | 1994 Aug | 7811395 |
| The mannose-permease of the bacterial phosphotransferase system. Gene cloning and purification of the enzyme IIMan/IIIMan complex of Escherichia coli. | Erni B, Zanolari B | 1985 Dec 15 | 2999119 |
| The mannose permease of Escherichia coli consists of three different proteins. Amino acid sequence and function in sugar transport, sugar phosphorylation, and penetration of phage lambda DNA. | Erni B, Zanolari B, Kocher HP | 1987 Apr 15 | 2951378 |
| Pel, the protein that permits lambda DNA penetration of Escherichia coli, is encoded by a gene in ptsM and is required for mannose utilization by the phosphotransferase system. | Williams N, Fox DK, Shea C, Roseman S | 1986 Dec | 2947241 |