Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.194
Description:Protein-N(pi)-phosphohistidine--L-ascorbate phosphotransferase.
Alternative Name: L-ascorbate PTS permease.
Prosite: PDOC00795;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.194
BRENDA Enzyme Link: BRENDA 2.7.1.194
KEGG Enzyme Link: KEGG2.7.1.194
BioCyc Enzyme Link: BioCyc 2.7.1.194
ExPASy Enzyme Link: ExPASy2.7.1.194
EC2PDB Enzyme Link: EC2PDB 2.7.1.194
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.194
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.194
IntEnz Enzyme Link: IntEnz 2.7.1.194
MEDLINE Enzyme Link: MEDLINE 2.7.1.194
MSA:

2.7.1.194;

Phylogenetic Tree:

2.7.1.194;

Uniprot:
M-CSA:
RHEA:42436 L-ascorbate(out) + N(pros)-phospho-L-histidyl-[protein] = L-ascorbate 6-phosphate(in) + L-histidyl-[protein]
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[n;H0;+0:7]1:[*:8]:[n;H0;+0:9]:[*:10]:[*:11]:1>>[*:8]1:[n;H0;+0:7]:[*:11]:[*:10]:[nH;+0:9]:1.[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystal structure of a phosphorylation-coupled vitamin C transporter.Luo P, Yu X, Wang W, Fan S, Li X, Wang J2015 Mar25686089
Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family.Hvorup R, Chang AB, Saier MH Jr200315153772
The ascorbate transporter of Escherichia coli.Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr2003 Apr12644495