EC number:2.7.1.197
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.197 | ||
|---|---|---|---|
| Description: | Protein-N(pi)-phosphohistidine--D-mannitol phosphotransferase. | ||
| Alternative Name: |
D-mannitol PTS permease. | ||
| Prosite: | PDOC00795; | ||
| PDB: |
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| Cath: | 3.40.930.10; 3.40.50.2300; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.197 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.197 |
| KEGG Enzyme Link: | KEGG2.7.1.197 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.197 |
| ExPASy Enzyme Link: | ExPASy2.7.1.197 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.197 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.197 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.197 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.197 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.197 |
EC number:2.7.1.197
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33363 | D-mannitol(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannitol 1-phosphate(in) + L-histidyl-[protein] |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[n;H0;+0:7]1:[*:8]:[n;H0;+0:9]:[*:10]:[*:11]:1>>[*:8]1:[n;H0;+0:7]:[*:11]:[*:10]:[nH;+0:9]:1.[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Relation between the oligomerization state and the transport and phosphorylation function of the Escherichia coli mannitol transport protein: interaction between mannitol-specific enzyme II monomers studied by complementation of inactive site-directed mutants. | Boer H, ten Hoeve-Duurkens RH, Robillard GT | 1996 Oct 1 | 8841134 |
| Substrate and phospholipid specificity of the purified mannitol permease of Escherichia coli. | Jacobson GR, Tanney LE, Kelly DM, Palman KB, Corn SB | 1983 | 6427236 |
| Mannitol-specific enzyme II of the bacterial phosphotransferase system. III. The nucleotide sequence of the permease gene. | Lee CA, Saier MH Jr | 1983 Sep 10 | 6309813 |
| Purification of the mannitol-specific enzyme II of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system. | Jacobson GR, Lee CA, Saier MH Jr | 1979 Jan 25 | 368051 |
| Functional reconstitution of the purified phosphoenolpyruvate-dependent mannitol-specific transport system of Escherichia coli in phospholipid vesicles: coupling between transport and phosphorylation. | Elferink MG, Driessen AJ, Robillard GT | 1990 Dec | 2123863 |
| Cytoplasmic phosphorylating domain of the mannitol-specific transport protein of the phosphoenolpyruvate-dependent phosphotransferase system in Escherichia coli: overexpression, purification, and functional complementation with the mannitol binding domain. | van Weeghel RP, Meyer G, Pas HH, Keck W, Robillard GT | 1991 Oct 1 | 1909895 |