EC number:2.7.1.199

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.199
Description:Protein-N(pi)-phosphohistidine--D-glucose phosphotransferase.
Alternative Name: D-glucose PTS permease.
Prosite: PDOC00795;
PDB:
PDBScop
Cath: 3.30.1360.60; 2.70.70.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.199
BRENDA Enzyme Link: BRENDA 2.7.1.199
KEGG Enzyme Link: KEGG2.7.1.199
BioCyc Enzyme Link: BioCyc 2.7.1.199
ExPASy Enzyme Link: ExPASy2.7.1.199
EC2PDB Enzyme Link: EC2PDB 2.7.1.199
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.199
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.199
IntEnz Enzyme Link: IntEnz 2.7.1.199
MEDLINE Enzyme Link: MEDLINE 2.7.1.199

EC number:2.7.1.199

MSA:

2.7.1.199;
Phylogenetic Tree:

2.7.1.199;
Uniprot:
M-CSA:
RHEA:33367 D-glucose(out) + N(pros)-phospho-L-histidyl-[protein] = D-glucose 6-phosphate(in) + L-histidyl-[protein]
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[n;H0;+0:7]1:[*:8]:[n;H0;+0:9]:[*:10]:[*:11]:1>>[*:8]1:[n;H0;+0:7]:[*:11]:[*:10]:[nH;+0:9]:1.[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Sugar transport by the bacterial phosphotransferase system. Isolation and characterization of a glucose-specific phosphocarrier protein (IIIGlc) from Salmonella typhimurium.Meadow ND, Roseman S1982 Dec 106754734
Sugar transport by the bacterial phosphotransferase system. The glucose receptors of the Salmonella typhimurium phosphotransferase system.Stock JB, Waygood EB, Meadow ND, Postma PW, Roseman S1982 Dec 106292227
Glucose permease of Escherichia coli. The effect of cysteine to serine mutations on the function, stability, and regulation of transport and phosphorylation.Nuoffer C, Zanolari B, Erni B1988 May 153129430
Glucose-permease of the bacterial phosphotransferase system. Gene cloning, overproduction, and amino acid sequence of enzyme IIGlc.Erni B, Zanolari B1986 Dec 153023349
Staphylococcal phosphoenolpyruvate-dependent phosphotransferase system--two highly similar glucose permeases in Staphylococcus carnosus with different glucoside specificity: protein engineering in vivo?Christiansen I, Hengstenberg W1999 Oct10537210