EC number:2.7.1.207
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.1 Phosphotransferases with an alcohol group as acceptor |
| ID: | 2.7.1.207 | ||
|---|---|---|---|
| Description: | Protein-N(pi)-phosphohistidine--lactose phosphotransferase. | ||
| Alternative Name: |
Lactose PTS permease. | ||
| Prosite: | PDOC00795; | ||
| PDB: |
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| Cath: | 1.20.58.80; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.1.207 |
| BRENDA Enzyme Link: | BRENDA 2.7.1.207 |
| KEGG Enzyme Link: | KEGG2.7.1.207 |
| BioCyc Enzyme Link: | BioCyc 2.7.1.207 |
| ExPASy Enzyme Link: | ExPASy2.7.1.207 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.1.207 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.1.207 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.1.207 |
| IntEnz Enzyme Link: | IntEnz 2.7.1.207 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.1.207 |
EC number:2.7.1.207
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42400 | lactose(out) + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + lactose 6-phosphate(in) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[n;H0;+0:7]1:[*:8]:[*:9]:[n;H0;+0:10]:[*:11]:1>>[*:1]-[O;H0;+0:2]-[P;H0;+0:4](=[*:3])(-[*:5])-[*:6].[*:8]1:[*:9]:[nH;+0:10]:[*:11]:[n;H0;+0:7]:1 |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Lactose-specific enzyme II of the phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus. Purification of the histidine-tagged transmembrane component IICBLac and its hydrophilic IIB domain by metal-affinity chromatography, and functional characterization. | Peters D, Frank R, Hengstenberg W | 1995 Mar 15 | 7737179 |
| Lactose transport in Streptococcus mutans: isolation and characterization of factor IIIlac, a specific protein component of the phosphoenolpyruvate-lactose phosphotransferase system. | Vadeboncoeur C, Proulx M | 1984 Oct | 6480107 |
| Identification of the genes for the lactose-specific components of the phosphotransferase system in the lac operon of Staphylococcus aureus. | Breidt F Jr, Hengstenberg W, Finkeldei U, Stewart GC | 1987 Dec 5 | 2824493 |
| Characterization of the lactose-specific enzymes of the phosphotransferase system in Lactococcus lactis. | de Vos WM, Boerrigter I, van Rooyen RJ, Reiche B, Hengstenberg W | 1990 Dec 25 | 2125052 |
| Solubilization of the membrane bound lactose specific component of the staphylococcal PEP dependant phosphotransferase system. | Hengstenberg W | 1970 Jun 27 | 11947593 |