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2. Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

ID:	2.7.1.35
Description:	Pyridoxal kinase.
Alternative Name:	Vitamin B6 kinase. Vitamin B(6) kinase. Pyridoxine kinase. Pyridoxamine kinase.
Cath:	3.40.1190.20;

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UniProtKB Enzyme Link:	UniProtKB 2.7.1.35
BRENDA Enzyme Link:	BRENDA 2.7.1.35
KEGG Enzyme Link:	KEGG2.7.1.35
BioCyc Enzyme Link:	BioCyc 2.7.1.35
ExPASy Enzyme Link:	ExPASy2.7.1.35
EC2PDB Enzyme Link:	EC2PDB 2.7.1.35
ExplorEnz Enzyme Link:	ExplorEnz 2.7.1.35
PRIAM enzyme-specific profiles Link:	PRIAM 2.7.1.35
IntEnz Enzyme Link:	IntEnz 2.7.1.35
MEDLINE Enzyme Link:	MEDLINE 2.7.1.35

RHEA:25108	ATP + pyridoxine = ADP + H(+) + pyridoxine 5'-phosphate
RULE(radius=1)	[:1]-[OH;+0:2].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:7]-[:8]>>[:8]-[OH;+0:7].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:2]-[:1]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Identification and function of the pdxY gene, which encodes a novel pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate biosynthesis in Escherichia coli K-12.	Yang Y, Tsui HC, Man TK, Winkler ME	1998 Apr	9537380
Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases.	di Salvo ML, Hunt S, Schirch V	2004 Aug	15249053
Pyridoxal phosphokinases. I. Assay, distribution, I. Assay, distribution, purification, and properties.	MCCORMICK DB, GREGORY ME, SNELL EE	1961 Jul	13773826

RHEA:25104	ATP + pyridoxamine = ADP + H(+) + pyridoxamine 5'-phosphate
RULE(radius=1)	[:1]-[OH;+0:2].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:7]-[:8]>>[:8]-[OH;+0:7].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:2]-[:1]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases.	di Salvo ML, Hunt S, Schirch V	2004 Aug	15249053
Pyridoxal phosphokinases. I. Assay, distribution, I. Assay, distribution, purification, and properties.	MCCORMICK DB, GREGORY ME, SNELL EE	1961 Jul	13773826

RHEA:10224	ATP + pyridoxal = ADP + H(+) + pyridoxal 5'-phosphate
RULE(radius=1)	[:1]-[OH;+0:2].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:7]-[:8]>>[:8]-[OH;+0:7].[:3]=[P;H0;+0:4](-[:5])(-[:6])-[O;H0;+0:2]-[:1]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Porcine pyridoxal kinase c-DNA cloning, expression and confirmation of its primary sequence.	Gao ZG, Lau CK, Lo SC, Choi SY, Churchich JE, Kwok F	1998 Dec	9924807
Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2methylpyrimidine kinase and pyridoxal kinase.	Park JH, Burns K, Kinsland C, Begley TP	2004 Mar	14973012
Identification and function of the pdxY gene, which encodes a novel pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate biosynthesis in Escherichia coli K-12.	Yang Y, Tsui HC, Man TK, Winkler ME	1998 Apr	9537380
Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases.	di Salvo ML, Hunt S, Schirch V	2004 Aug	15249053
Pyridoxal phosphokinases. I. Assay, distribution, I. Assay, distribution, purification, and properties.	MCCORMICK DB, GREGORY ME, SNELL EE	1961 Jul	13773826