EC number:2.7.1.36

Enzyme

Download
EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.36
Description:Mevalonate kinase.
Prosite: PDOC00545;
PDB:
PDBScop
Cath: 3.30.230.10; 3.30.70.890;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.36
BRENDA Enzyme Link: BRENDA 2.7.1.36
KEGG Enzyme Link: KEGG2.7.1.36
BioCyc Enzyme Link: BioCyc 2.7.1.36
ExPASy Enzyme Link: ExPASy2.7.1.36
EC2PDB Enzyme Link: EC2PDB 2.7.1.36
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.36
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.36
IntEnz Enzyme Link: IntEnz 2.7.1.36
MEDLINE Enzyme Link: MEDLINE 2.7.1.36

EC number:2.7.1.36

MSA:

2.7.1.36;
Phylogenetic Tree:

2.7.1.36;
Uniprot:
M-CSA:
RHEA:17065 (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways.Hinson DD, Chambliss KL, Toth MJ, Tanaka RD, Gibson KM1997 Nov9392419