EC number:2.7.1.45

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.45
Description:2-dehydro-3-deoxygluconokinase.
Alternative Name: KDG kinase.
3-deoxy-2-oxo-D-gluconate kinase.
2-keto-3-deoxygluconokinase.
Prosite: PDOC00504;
PDB:
PDBScop
Cath: 3.40.1190.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.45
BRENDA Enzyme Link: BRENDA 2.7.1.45
KEGG Enzyme Link: KEGG2.7.1.45
BioCyc Enzyme Link: BioCyc 2.7.1.45
ExPASy Enzyme Link: ExPASy2.7.1.45
EC2PDB Enzyme Link: EC2PDB 2.7.1.45
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.45
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.45
IntEnz Enzyme Link: IntEnz 2.7.1.45
MEDLINE Enzyme Link: MEDLINE 2.7.1.45

EC number:2.7.1.45

MSA:

2.7.1.45;
Phylogenetic Tree:

2.7.1.45;
Uniprot:
M-CSA:
RHEA:14797 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of Sulfolobus solfataricus 2-keto-3-deoxy-D-gluconate kinase in the modified Entner-Doudoroff pathway.Kim S, Lee SB2006 Jun16794308
Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus.Lamble HJ, Theodossis A, Milburn CC, Taylor GL, Bull SD, Hough DW, Danson MJ2005 Dec 1916330030
Uronic acid metabolism in bacteria. IV. Purification and properties of 2-keto-3-deoxy-D-gluconokinase in Escherichia coli.CYNKIN MA, ASHWELL G1960 Jun13813474
Prediction of enzymatic pathways by integrative pathway mapping.Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A2018 Jan 2929377793