EC number:2.7.1.50

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.50
Description:Hydroxyethylthiazole kinase.
Cath: 3.40.1190.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.50
BRENDA Enzyme Link: BRENDA 2.7.1.50
KEGG Enzyme Link: KEGG2.7.1.50
BioCyc Enzyme Link: BioCyc 2.7.1.50
ExPASy Enzyme Link: ExPASy2.7.1.50
EC2PDB Enzyme Link: EC2PDB 2.7.1.50
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.50
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.50
IntEnz Enzyme Link: IntEnz 2.7.1.50
MEDLINE Enzyme Link: MEDLINE 2.7.1.50

EC number:2.7.1.50

MSA:

2.7.1.50;
Phylogenetic Tree:

2.7.1.50;
Uniprot:
M-CSA:
RHEA:24212 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of the Bacillus subtilis thiC operon involved in thiamine biosynthesis.Zhang Y, Taylor SV, Chiu HJ, Begley TP1997 May9139923
The thiM locus and its relation to phosphorylation of hydroxyethylthiazole in Escherichia coli.Mizote T, Nakayama H1989 Jun2542220
Identification of the thiamin salvage enzyme thiazole kinase in Arabidopsis and maize.Yazdani M, Zallot R, Tunc-Ozdemir M, de Crécy-Lagard V, Shintani DK, Hanson AD2013 Oct23816351