EC number:2.7.11.15
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.11 Protein-serine/threonine kinases |
| ID: | 2.7.11.15 | ||
|---|---|---|---|
| Description: | [Beta-adrenergic-receptor] kinase. | ||
| Alternative Name: |
Beta-receptor kinase. Beta-ARK. Beta-AR kinase. Beta-adrenoceptor kinase. Beta-adrenergic-receptor kinase (phosphorylating). Beta-adrenergic-receptor kinase. Beta-adrenergic receptor-specific kinase. Beta(2)ARK. BARK1. Adrenergic receptor kinase. ADRBK1. | ||
| Prosite: | PDOC00100; | ||
| PDB: |
|
||
| Cath: | 1.10.167.10; 1.10.287.1270; 1.10.510.10; 1.20.5.40; 1.20.5.4070; 3.30.200.20; 1.20.58.1850; 2.30.29.30; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.11.15 |
| BRENDA Enzyme Link: | BRENDA 2.7.11.15 |
| KEGG Enzyme Link: | KEGG2.7.11.15 |
| BioCyc Enzyme Link: | BioCyc 2.7.11.15 |
| ExPASy Enzyme Link: | ExPASy2.7.11.15 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.11.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.11.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.11.15 |
| IntEnz Enzyme Link: | IntEnz 2.7.11.15 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.11.15 |
EC number:2.7.11.15
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:19429 | [beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization and inhibition of beta-adrenergic receptor kinase in intact myocytes. | Laugwitz KL, Kronsbein K, Schmitt M, Hoffmann K, Seyfarth M, Schömig A, Ungerer M | 1997 Aug | 9349395 |
| Expression and characterization of two beta-adrenergic receptor kinase isoforms using the baculovirus expression system. | Kim CM, Dion SB, Onorato JJ, Benovic JL | 1993 Spring | 8394172 |
| Purification and characterization of the beta-adrenergic receptor kinase. | Benovic JL, Mayor F Jr, Staniszewski C, Lefkowitz RJ, Caron MG | 1987 Jul 5 | 3036840 |