EC number:2.7.11.27

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.11 Protein-serine/threonine kinases
ID:2.7.11.27
Description:[Acetyl-CoA carboxylase] kinase.
Alternative Name: I-peptide kinase.
AMPK.
Acetyl-coenzyme A carboxylase kinase.
Acetyl-CoA carboxylase kinase (cAMP-independent).
Acetyl-CoA carboxylase kinase (AMP-activated).
Acetyl-CoA carboxylase kinase.
Acetyl-CoA carboxylase bound kinase.
Acetyl coenzyme A carboxylase kinase (phosphorylating).
Cath: 1.10.510.10; 1.10.8.10; 1.10.800.10; 3.30.200.20; 3.30.310.80; 3.30.70.260;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.11.27
BRENDA Enzyme Link: BRENDA 2.7.11.27
KEGG Enzyme Link: KEGG2.7.11.27
BioCyc Enzyme Link: BioCyc 2.7.11.27
ExPASy Enzyme Link: ExPASy2.7.11.27
EC2PDB Enzyme Link: EC2PDB 2.7.11.27
ExplorEnz Enzyme Link: ExplorEnz 2.7.11.27
PRIAM enzyme-specific profiles Link: PRIAM 2.7.11.27
IntEnz Enzyme Link: IntEnz 2.7.11.27
MEDLINE Enzyme Link: MEDLINE 2.7.11.27

EC number:2.7.11.27

MSA:

2.7.11.27;
Phylogenetic Tree:

2.7.11.27;
Uniprot:
M-CSA:
RHEA:20333 [acetyl-CoA carboxylase]-L-serine + ATP = [acetyl-CoA carboxylase]-O-phospho-L-serine + ADP + H(+)
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterisation of an insulin-stimulated protein-serine kinase which phosphorylates acetyl-CoA carboxylase.Heesom KJ, Moule SK, Denton RM1998 Jan 239475166
Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A.Winder WW, Wilson HA, Hardie DG, Rasmussen BB, Hutber CA, Call GB, Clayton RD, Conley LM, Yoon S, Zhou B1997 Jan9029219
Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity.Munday MR, Hardie DG1984 Jun 156146523
Purification and properties of a kinase which phosphorylates and inactivates acetyl-CoA carboxylase.Lent B, Kim KH1982 Feb 256120170