EC number:2.7.11.7
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.11 Protein-serine/threonine kinases |
| ID: | 2.7.11.7 | ||||||||||||||||||||||||||||||
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| Description: | [Myosin heavy-chain] kinase. | ||||||||||||||||||||||||||||||
| Alternative Name: |
Myosin II heavy-chain kinase. Myosin I heavy-chain kinase. Myosin heavy-chain kinase. Myosin heavy chain kinase A. Myosin heavy chain kinase. MIHC kinase. MHCK. Calmodulin-dependent myosin heavy chain kinase. | ||||||||||||||||||||||||||||||
| Prosite: | PDOC51158; PDOC00100; | ||||||||||||||||||||||||||||||
| PDB: |
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| Cath: | 3.20.200.10; 3.30.200.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.11.7 |
| BRENDA Enzyme Link: | BRENDA 2.7.11.7 |
| KEGG Enzyme Link: | KEGG2.7.11.7 |
| BioCyc Enzyme Link: | BioCyc 2.7.11.7 |
| ExPASy Enzyme Link: | ExPASy2.7.11.7 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.11.7 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.11.7 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.11.7 |
| IntEnz Enzyme Link: | IntEnz 2.7.11.7 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.11.7 |
| RHEA:11424 | [myosin heavy-chain]-L-threonine + ATP = [myosin heavy-chain]-O-phospho-L-threonine + ADP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of a myosin I heavy chain kinase from Acanthamoeba castellanii. | Hammer JA 3rd, Albanesi JP, Korn ED | 1983 Aug 25 | 6309772 |
| Purification and characterization of a myosin heavy chain kinase from Dictyostelium discoideum. | Côte GP, Bukiejko U | 1987 Jan 25 | 3027076 |
| Purification and characterization of a calmodulin-dependent myosin heavy chain kinase from intestinal brush border. | Rieker JP, Swanljung-Collins H, Collins JH | 1987 Nov 5 | 2822719 |
| Myosin heavy chain kinase from developed Dictyostelium cells. Purification and characterization. | Ravid S, Spudich JA | 1989 Sep 5 | 2549052 |
| Substrate specificity of Acanthamoeba myosin I heavy chain kinase as determined with synthetic peptides. | Brzeska H, Lynch TJ, Martin B, Corigliano-Murphy A, Korn ED | 1990 Sep 25 | 2168881 |
| Membrane-bound Dictyostelium myosin heavy chain kinase: a developmentally regulated substrate-specific member of the protein kinase C family. | Ravid S, Spudich JA | 1992 Jul 1 | 1321427 |