EC number:2.7.2.15
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.2 Phosphotransferases with a carboxy group as acceptor |
| ID: | 2.7.2.15 | ||
|---|---|---|---|
| Description: | Propionate kinase. | ||
| Alternative Name: |
Propionate/acetate kinase. | ||
| Prosite: | PDOC00826; | ||
| PDB: |
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| Cath: | 3.30.420.40; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.2.15 |
| BRENDA Enzyme Link: | BRENDA 2.7.2.15 |
| KEGG Enzyme Link: | KEGG2.7.2.15 |
| BioCyc Enzyme Link: | BioCyc 2.7.2.15 |
| ExPASy Enzyme Link: | ExPASy2.7.2.15 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.2.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.2.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.2.15 |
| IntEnz Enzyme Link: | IntEnz 2.7.2.15 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.2.15 |
| RHEA:23148 | ATP + propanoate = ADP + propanoyl phosphate |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate. | Hesslinger C, Fairhurst SA, Sawers G | 1998 Jan | 9484901 |
| Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of propionate kinase (TdcD) from Salmonella typhimurium. | Simanshu DK, Murthy MR | 2005 Jan 1 | 16508089 |
| Crystal structures of ADP and AMPPNP-bound propionate kinase (TdcD) from Salmonella typhimurium: comparison with members of acetate and sugar kinase/heat shock cognate 70/actin superfamily. | Simanshu DK, Savithri HS, Murthy MR | 2005 Sep 30 | 16139298 |
| Propionyl coenzyme A is a common intermediate in the 1,2-propanediol and propionate catabolic pathways needed for expression of the prpBCDE operon during growth of Salmonella enterica on 1,2-propanediol. | Palacios S, Starai VJ, Escalante-Semerena JC | 2003 May | 12700259 |