Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.4 Phosphotransferases with a phosphate group as acceptor
ID:2.7.4.1
Description:Polyphosphate kinase.
Alternative Name: Polyphosphoric acid kinase.
ATP-polyphosphate phosphotransferase.
Cath: 3.30.1840.10; 3.30.870.10; 1.20.58.310;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.4.1
BRENDA Enzyme Link: BRENDA 2.7.4.1
KEGG Enzyme Link: KEGG2.7.4.1
BioCyc Enzyme Link: BioCyc 2.7.4.1
ExPASy Enzyme Link: ExPASy2.7.4.1
EC2PDB Enzyme Link: EC2PDB 2.7.4.1
ExplorEnz Enzyme Link: ExplorEnz 2.7.4.1
PRIAM enzyme-specific profiles Link: PRIAM 2.7.4.1
IntEnz Enzyme Link: IntEnz 2.7.4.1
MEDLINE Enzyme Link: MEDLINE 2.7.4.1
MSA:

2.7.4.1;

Phylogenetic Tree:

2.7.4.1;

Uniprot:
M-CSA:
RHEA:19573 [phosphate](n) + ATP = [phosphate](n+1) + ADP
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Phosphohistidyl active sites in polyphosphate kinase of Escherichia coli.Kumble KD, Ahn K, Kornberg A1996 Dec 108962061
Pseudomonas aeruginosa Exopolyphosphatase Is Also a Polyphosphate: ADP Phosphotransferase.Beassoni PR, Gallarato LA, Boetsch C, Garrido MN, Lisa AT201526576296
Degradation of polyphosphates by polyphosphate kinases from Ruegeria pomeroyi.Achbergerová L, Nahálka J2014 Oct24930102
A new subfamily of polyphosphate kinase 2 (class III PPK2) catalyzes both nucleoside monophosphate phosphorylation and nucleoside diphosphate phosphorylation.Motomura K, Hirota R, Okada M, Ikeda T, Ishida T, Kuroda A2014 Apr24532069
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria.Nocek B, Kochinyan S, Proudfoot M, Brown G, Evdokimova E, Osipiuk J, Edwards AM, Savchenko A, Joachimiak A, Yakunin AF2008 Nov 1819001261
NCgl2620 encodes a class II polyphosphate kinase in Corynebacterium glutamicum.Lindner SN, Vidaurre D, Willbold S, Schoberth SM, Wendisch VF2007 Aug17545325
The polyphosphate kinase gene of Escherichia coli. Isolation and sequence of the ppk gene and membrane location of the protein.Akiyama M, Crooke E, Kornberg A1992 Nov 51331061
A polyphosphate kinase (PPK2) widely conserved in bacteria.Zhang H, Ishige K, Kornberg A2002 Dec 2412486232
Polyphosphate kinase (PPK2), a potent, polyphosphate-driven generator of GTP.Ishige K, Zhang H, Kornberg A2002 Dec 2412482933
The multiple activities of polyphosphate kinase of Escherichia coli and their subunit structure determined by radiation target analysis.Tzeng CM, Kornberg A2000 Feb 1110660553
The polyphosphate kinase gene of Pseudomonas aeruginosa.Ishige K, Kameda A, Noguchi T, Shiba T1998 Jun 309734809
Cloning and characterization of polyphosphate kinase and exopolyphosphatase genes from Pseudomonas aeruginosa 8830.Zago A, Chugani S, Chakrabarty AM1999 May10224002