EC number:2.7.4.12
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.4 Phosphotransferases with a phosphate group as acceptor |
| ID: | 2.7.4.12 |
|---|---|
| Description: | T(2)-induced deoxynucleotide kinase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.4.12 |
| BRENDA Enzyme Link: | BRENDA 2.7.4.12 |
| KEGG Enzyme Link: | KEGG2.7.4.12 |
| BioCyc Enzyme Link: | BioCyc 2.7.4.12 |
| ExPASy Enzyme Link: | ExPASy2.7.4.12 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.4.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.4.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.4.12 |
| IntEnz Enzyme Link: | IntEnz 2.7.4.12 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.4.12 |
| RHEA:13517 | ATP + dTMP = ADP + dTDP |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation and characterization of an Escherichia coli mutant deficient in dTMP kinase activity. | Daws TD, Fuchs JA | 1984 Feb | 6319360 |
| Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes. | Munier-Lehmann H, Chaffotte A, Pochet S, Labesse G | 2001 Jun | 11369858 |
| RHEA:12697 | ATP + dGMP = ADP + dGDP |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of guanylate kinase from Escherichia coli. | Oeschger MP, Bessman MJ | 1966 Nov 25 | 5333666 |
| Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G. | Hible G, Daalova P, Gilles AM, Cherfils J | 2006 Sep | 16690197 |
| Cloning of the guanylate kinase homologues AGK-1 and AGK-2 from Arabidopsis thaliana and characterization of AGK-1. | Kumar V, Spangenberg O, Konrad M | 2000 Jan | 10632732 |