EC number:2.7.4.22

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.4 Phosphotransferases with a phosphate group as acceptor
ID:2.7.4.22
Description:UMP kinase.
Alternative Name: Uridylate kinase.
Uridine monophosphate kinase.
UMPK.
UMP-kinase.
Cath: 3.40.1160.10; 3.40.50.300;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.4.22
BRENDA Enzyme Link: BRENDA 2.7.4.22
KEGG Enzyme Link: KEGG2.7.4.22
BioCyc Enzyme Link: BioCyc 2.7.4.22
ExPASy Enzyme Link: ExPASy2.7.4.22
EC2PDB Enzyme Link: EC2PDB 2.7.4.22
ExplorEnz Enzyme Link: ExplorEnz 2.7.4.22
PRIAM enzyme-specific profiles Link: PRIAM 2.7.4.22
IntEnz Enzyme Link: IntEnz 2.7.4.22
MEDLINE Enzyme Link: MEDLINE 2.7.4.22

EC number:2.7.4.22

MSA:

2.7.4.22;
Phylogenetic Tree:

2.7.4.22;
Uniprot:
M-CSA:
RHEA:24400 ATP + UMP = ADP + UDP
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis.Marco-Marín C, Gil-Ortiz F, Rubio V2005 Sep 1616095620