EC number:2.7.4.3

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.4 Phosphotransferases with a phosphate group as acceptor
ID:2.7.4.3
Description:Adenylate kinase.
Alternative Name: Myokinase.
Adenylokinase.
Adenylic kinase.
Prosite: PDOC00104;
PDB:
PDBScop
5UKD 8058387; 8058388;
4UKD 8058387; 8058388;
3UKD 8058387; 8058388;
2UKD 8058387; 8058388;
1UKE 8058387; 8058388;
 » show all
Cath: 1.20.5.4220; 3.40.50.300;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.4.3
BRENDA Enzyme Link: BRENDA 2.7.4.3
KEGG Enzyme Link: KEGG2.7.4.3
BioCyc Enzyme Link: BioCyc 2.7.4.3
ExPASy Enzyme Link: ExPASy2.7.4.3
EC2PDB Enzyme Link: EC2PDB 2.7.4.3
ExplorEnz Enzyme Link: ExplorEnz 2.7.4.3
PRIAM enzyme-specific profiles Link: PRIAM 2.7.4.3
IntEnz Enzyme Link: IntEnz 2.7.4.3
MEDLINE Enzyme Link: MEDLINE 2.7.4.3

EC number:2.7.4.3

MSA:

2.7.4.3;
Phylogenetic Tree:

2.7.4.3;
Uniprot:
M-CSA:
RHEA:12973 AMP + ATP = 2 ADP
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Yeast adenylate kinase is active simultaneously in mitochondria and cytoplasm and is required for non-fermentative growth.Bandlow W, Strobel G, Zoglowek C, Oechsner U, Magdolen V1988 Dec 152850178
The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes.Panayiotou C, Solaroli N, Xu Y, Johansson M, Karlsson A2011 Feb 121080915
Functions of chloroplastic adenylate kinases in Arabidopsis.Lange PR, Geserick C, Tischendorf G, Zrenner R2008 Feb18162585
Maize leaf adenylate kinase : purification and partial characterization.Kleczkowski LA, Randall DD1986 Aug16664952
The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus.Ren H, Wang L, Bennett M, Liang Y, Zheng X, Lu F, Li L, Nan J, Luo M, Eriksson S, Zhang C, Su XD2005 Jan 1115630091
A new subfamily of short bacterial adenylate kinases with the Mycobacterium tuberculosis enzyme as a model: A predictive and experimental study.Munier-Lehmann H, Burlacu-Miron S, Craescu CT, Mantsch HH, Schultz CP1999 Aug 110398370
The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.Amiri M, Conserva F, Panayiotou C, Karlsson A, Solaroli N2013 May23416111