| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.6 Diphosphotransferases |
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| UniProtKB Enzyme Link: | UniProtKB 2.7.6.3 |
| BRENDA Enzyme Link: | BRENDA 2.7.6.3 |
| KEGG Enzyme Link: | KEGG2.7.6.3 |
| BioCyc Enzyme Link: | BioCyc 2.7.6.3 |
| ExPASy Enzyme Link: | ExPASy2.7.6.3 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.6.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.6.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.6.3 |
| IntEnz Enzyme Link: | IntEnz 2.7.6.3 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.6.3 |
| RHEA:11412 | 6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:7]-[O;H0;+0:8]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A bifunctional protein in the folate biosynthetic pathway of Streptococcus pneumoniae with dihydroneopterin aldolase and hydroxymethyldihydropterin pyrophosphokinase activities. | Lopez P, Lacks SA | 1993 Apr | 8385663 |
| The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid. | Richey DP, Brown GM | 1969 Mar 25 | 4304228 |
| DNA sequence of folate biosynthesis gene sulD, encoding hydroxymethyldihydropterin pyrophosphokinase in Streptococcus pneumoniae, and characterization of the enzyme. | Lopez P, Greenberg B, Lacks SA | 1990 Sep | 2168367 |
| Purification and partial characterization of 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase and 7,8-dihydropteroate synthase from Escherichia coli MC4100. | Talarico TL, Dev IK, Dallas WS, Ferone R, Ray PH | 1991 Nov | 1657875 |
| Characterization of the Saccharomyces cerevisiae Fol1 protein: starvation for C1 carrier induces pseudohyphal growth. | Güldener U, Koehler GJ, Haussmann C, Bacher A, Kricke J, Becher D, Hegemann JH | 2004 Aug | 15169867 |