EC number:2.7.7.100

Enzyme

Download
EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.100
Description:SAMP-activating enzyme.
Alternative Name: SAMP-activating enzyme E1.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.100
BRENDA Enzyme Link: BRENDA 2.7.7.100
KEGG Enzyme Link: KEGG2.7.7.100
BioCyc Enzyme Link: BioCyc 2.7.7.100
ExPASy Enzyme Link: ExPASy2.7.7.100
EC2PDB Enzyme Link: EC2PDB 2.7.7.100
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.100
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.100
IntEnz Enzyme Link: IntEnz 2.7.7.100
MEDLINE Enzyme Link: MEDLINE 2.7.7.100

EC number:2.7.7.100

MSA:

2.7.7.100;
Phylogenetic Tree:

2.7.7.100;
Uniprot:
M-CSA:
RHEA:56100 [small archaeal modifier protein]-C-terminal Gly-Gly + ATP + H(+) = [small archaeal modifier protein]-C-terminal Gly-Gly-AMP + diphosphate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8].[H+;H0:9]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea.Hepowit NL, de Vera IM, Cao S, Fu X, Wu Y, Uthandi S, Chavarria NE, Englert M, Su D, Sӧll D, Kojetin DJ, Maupin-Furlow JA2016 Oct27459543
Ubiquitin-like proteins and their roles in archaea.Maupin-Furlow JA2013 Jan23140889
Archaeal ubiquitin-like SAMP3 is isopeptide-linked to proteins via a UbaA-dependent mechanism.Miranda HV, Antelmann H, Hepowit N, Chavarria NE, Krause DJ, Pritz JR, Bäsell K, Becher D, Humbard MA, Brocchieri L, Maupin-Furlow JA2014 Jan24097257
E1- and ubiquitin-like proteins provide a direct link between protein conjugation and sulfur transfer in archaea.Miranda HV, Nembhard N, Su D, Hepowit N, Krause DJ, Pritz JR, Phillips C, Söll D, Maupin-Furlow JA2011 Mar 1521368171
Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii.Humbard MA, Miranda HV, Lim JM, Krause DJ, Pritz JR, Zhou G, Chen S, Wells L, Maupin-Furlow JA2010 Jan 720054389