EC number:2.7.7.31
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.7 Nucleotidyltransferases |
| ID: | 2.7.7.31 | ||
|---|---|---|---|
| Description: | DNA nucleotidylexotransferase. | ||
| Alternative Name: |
Terminal transferase. Terminal deoxyribonucleotidyltransferase. Terminal deoxynucleotidyltransferase. Terminal addition enzyme. | ||
| Prosite: | PDOC00452; | ||
| PDB: |
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| Cath: | 1.10.150.110; 1.10.150.20; 3.30.210.10; 3.30.460.10; 3.40.50.10190; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.7.31 |
| BRENDA Enzyme Link: | BRENDA 2.7.7.31 |
| KEGG Enzyme Link: | KEGG2.7.7.31 |
| BioCyc Enzyme Link: | BioCyc 2.7.7.31 |
| ExPASy Enzyme Link: | ExPASy2.7.7.31 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.7.31 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.7.31 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.7.31 |
| IntEnz Enzyme Link: | IntEnz 2.7.7.31 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.7.31 |
| RHEA:22508 | a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].([*:7]-[OH;+0:8].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[O;H0;+0:13]-[*:14])>>([*:7]-[O;H0;+0:8]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[O;H0;+0:2]-[*:1]).[*:14]-[OH;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The terminal nucleotidyltransferases of calf thymus nuclei. | Gottesman ME, Canellakis ES | 1966 Oct 10 | 4288534 |
| Studies on the incorporation of deoxyribonucleic acid. | KRAKOW JS, COUTSOGEORGOPOULOS C, CANELLAKIS ES | 1962 May 14 | 14459258 |
| Biochemical studies of bacterial sporulation. II. Deoxy- ribonucleic acid polymerase in spores of Bacillus subtilis. | Falaschi A, Kornberg A | 1966 Apr 10 | 4957767 |
| RNA-dependent DNA polymerase in virions of Rous sarcoma virus. | Temin HM, Mizutani S | 1970 Jun 27 | 4316301 |
| RNA-dependent DNA polymerase in virions of RNA tumour viruses. | Baltimore D | 1970 Jun 27 | 4316300 |
| Enzymatic synthesis of deoxyribonucleic acid. I. Preparation of substrates and partial purification of an enzyme from Escherichia coli. | LEHMAN IR, BESSMAN MJ, SIMMS ES, KORNBERG A | 1958 Jul | 13563462 |