EC number:2.7.7.42
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.7 Nucleotidyltransferases |
| ID: | 2.7.7.42 |
|---|---|
| Description: | [Glutamine synthetase] adenylyltransferase. |
| Alternative Name: |
Glutamine-synthetase adenylyltransferase. Glutamate-ammonia-ligase adenylyltransferase. [Glutamate--ammonia-ligase] adenylyltransferase. |
| Cath: | 1.10.4050.10; 1.20.120.1510; 1.20.120.330; 3.30.460.10; 3.30.460.100; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.7.42 |
| BRENDA Enzyme Link: | BRENDA 2.7.7.42 |
| KEGG Enzyme Link: | KEGG2.7.7.42 |
| BioCyc Enzyme Link: | BioCyc 2.7.7.42 |
| ExPASy Enzyme Link: | ExPASy2.7.7.42 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.7.42 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.7.42 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.7.42 |
| IntEnz Enzyme Link: | IntEnz 2.7.7.42 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.7.42 |
| RHEA:18589 | [glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| ATP: glutamine synthetase adenylyltransferase from Escherichia coli B. Purification and properties. | Ebner E, Wolf D, Gancedo C, Elsässer S, Holzer H | 1970 Jul | 4920894 |
| Regulation of glutamine synthetase. 8. ATP: glutamine synthetase adenylyltransferase, an enzyme that catalyzes alterations in the regulatory properties of glutamine synthetase. | Kingdon HS, Shapiro BM, Stadtman ER | 1967 Oct | 4867671 |
| Mechanism of the enzymatic inactivation of glutamine synthetase from E. coli. | Wulff K, Mecke D, Holzer H | 1967 Sep 7 | 4861255 |
| Inactivation, stabilization and some properties of ATP: glutamine synthetase adenylyltransferase from Escherichia coli B. | Wolf D, Ebner E, Hinze H | 1972 Feb 15 | 4402680 |
| 5'-adenylyl-O-tyrosine. The novel phosphodiester residue of adenylylated glutamine synthetase from Escherichia coli. | Shapiro BM, Stadtman ER | 1968 Jul 10 | 4298074 |
| Reversible adenylylation of glutamine synthetase is dynamically counterbalanced during steady-state growth of Escherichia coli. | Okano H, Hwa T, Lenz P, Yan D | 2010 Dec 3 | 20887734 |