EC number:2.7.7.53

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.53
Description:ATP adenylyltransferase.
Alternative Name: Diadenosinetetraphosphate alpha-beta-phosphorylase.
Diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase.
Bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming).
AP-4-A phosphorylase.
Cath: 3.30.428.10; 3.30.428.70;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.53
BRENDA Enzyme Link: BRENDA 2.7.7.53
KEGG Enzyme Link: KEGG2.7.7.53
BioCyc Enzyme Link: BioCyc 2.7.7.53
ExPASy Enzyme Link: ExPASy2.7.7.53
EC2PDB Enzyme Link: EC2PDB 2.7.7.53
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.53
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.53
IntEnz Enzyme Link: IntEnz 2.7.7.53
MEDLINE Enzyme Link: MEDLINE 2.7.7.53

EC number:2.7.7.53

MSA:

2.7.7.53;
Phylogenetic Tree:

2.7.7.53;
Uniprot:
M-CSA:
RHEA:16577 ADP + ATP + H(+) = P(1),P(4)-bis(5'-adenosyl)tetraphosphate + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:7]-[OH;+0:8].[H+;H0:9]>>[*:7]-[O;H0;+0:8]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Phosphorolytic cleavage of diadenosine 5',5'''-P1,P4-tetraphosphate. Properties of homogeneous diadenosine 5',5'''-P1,P4-tetraphosphate alpha, beta-phosphorylase from Saccharomyces cerevisiae.Guranowski A, Blanquet S1985 Mar 252982863
Structural insights into the novel diadenosine 5',5‴-P¹,P⁴-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv.Mori S, Shibayama K, Wachino J, Arakawa Y2011 Jul 121565198