EC number:2.7.7.77

Enzyme

Download
EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.77
Description:Molybdenum cofactor guanylyltransferase.
Alternative Name: MoCo guanylyltransferase.
Cath: 3.90.550.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.77
BRENDA Enzyme Link: BRENDA 2.7.7.77
KEGG Enzyme Link: KEGG2.7.7.77
BioCyc Enzyme Link: BioCyc 2.7.7.77
ExPASy Enzyme Link: ExPASy2.7.7.77
EC2PDB Enzyme Link: EC2PDB 2.7.7.77
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.77
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.77
IntEnz Enzyme Link: IntEnz 2.7.7.77
MEDLINE Enzyme Link: MEDLINE 2.7.7.77

EC number:2.7.7.77

MSA:

2.7.7.77;
Phylogenetic Tree:

2.7.7.77;
Uniprot:
M-CSA:
RHEA:34243 GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:7]-[*:8].[H+;H0:9]>>[*:8]-[OH;+0:7].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA.Guse A, Stevenson CE, Kuper J, Buchanan G, Schwarz G, Giordano G, Magalon A, Mendel RR, Lawson DM, Palmer T2003 Jul 1112719427
Mechanism of assembly of the Bis(Molybdopterin guanine dinucleotide)molybdenum cofactor in Rhodobacter sphaeroides dimethyl sulfoxide reductase.Temple CA, Rajagopalan KV2000 Dec 2210978348
The crystal structure of the Escherichia coli MobA protein provides insight into molybdopterin guanine dinucleotide biosynthesis.Lake MW, Temple CA, Rajagopalan KV, Schindelin H2000 Dec 2210978347