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2. Transferases

2.7 Transferring phosphorus-containing groups

2.7.7 Nucleotidyltransferases

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UniProtKB Enzyme Link:	UniProtKB 2.7.7.86
BRENDA Enzyme Link:	BRENDA 2.7.7.86
KEGG Enzyme Link:	KEGG2.7.7.86
BioCyc Enzyme Link:	BioCyc 2.7.7.86
ExPASy Enzyme Link:	ExPASy2.7.7.86
EC2PDB Enzyme Link:	EC2PDB 2.7.7.86
ExplorEnz Enzyme Link:	ExplorEnz 2.7.7.86
PRIAM enzyme-specific profiles Link:	PRIAM 2.7.7.86
IntEnz Enzyme Link:	IntEnz 2.7.7.86
MEDLINE Enzyme Link:	MEDLINE 2.7.7.86

RHEA:42064	ATP + GTP = cyclic G(2'-5')pA(3'-5')p + 2 diphosphate
RULE(radius=1)	([:1]-[O;H0;+0:2]-[P;H0;+0:3](=[:4])(-[:5])-[:6].[:7]-[OH;+0:8]).([:9]-[OH;+0:10].[:11]-[P;H0;+0:12](=[:13])(-[:14])-[O;H0;+0:15]-[:16])>>([:9]-[O;H0;+0:10]-[P;H0;+0:3](=[:4])(-[:5])-[:6].[:11]-[P;H0;+0:12](=[:13])(-[:14])-[O;H0;+0:8]-[:7]).[:16]-[OH;+0:15].[:1]-[OH;+0:2]
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Title	Authors	Date	PubMed ID
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.	Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE	2015 Sep 17	26300263
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.	Ablasser A, Goldeck M, Cavlar T, Deimling T, Witte G, Röhl I, Hopfner KP, Ludwig J, Hornung V	2013 Jun 20	23722158
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.	Sun L, Wu J, Du F, Chen X, Chen ZJ	2013 Feb 15	23258413