EC number:2.7.8.11
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.8 Transferases for other substituted phosphate groups |
| ID: | 2.7.8.11 | ||
|---|---|---|---|
| Description: | CDP-diacylglycerol--inositol 3-phosphatidyltransferase. | ||
| Alternative Name: |
Phosphatidylinositol synthase. CDP-diacylglycerol--inositol phosphatidyltransferase. | ||
| Prosite: | PDOC00321; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.8.11 |
| BRENDA Enzyme Link: | BRENDA 2.7.8.11 |
| KEGG Enzyme Link: | KEGG2.7.8.11 |
| BioCyc Enzyme Link: | BioCyc 2.7.8.11 |
| ExPASy Enzyme Link: | ExPASy2.7.8.11 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.8.11 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.8.11 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.8.11 |
| IntEnz Enzyme Link: | IntEnz 2.7.8.11 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.8.11 |
| RHEA:11580 | a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of phosphatidylinositol synthase from human placenta. | Antonsson BE | 1994 Feb 1 | 8110188 |
| Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein. | Monaco ME, Feldman M, Kleinberg DL | 1994 Nov 15 | 7998949 |
| Regulation by phosphatidylinositol of rat pituitary plasma membrane and endoplasmic reticulum phosphatidylinositol synthase activities. A mechanism for activation of phosphoinositide resynthesis during cell stimulation. | Imai A, Gershengorn MC | 1987 May 15 | 3032971 |
| Identification of AtPIS, a phosphatidylinositol synthase from Arabidopsis. | Collin S, Justin AM, Cantrel C, Arondel V, Kader JC | 1999 Jun | 10411624 |