EC number:2.7.8.24
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.8 Transferases for other substituted phosphate groups |
| ID: | 2.7.8.24 |
|---|---|
| Description: | Phosphatidylcholine synthase. |
| Alternative Name: |
PC synthase. CDP-diglyceride-choline O-phosphatidyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.8.24 |
| BRENDA Enzyme Link: | BRENDA 2.7.8.24 |
| KEGG Enzyme Link: | KEGG2.7.8.24 |
| BioCyc Enzyme Link: | BioCyc 2.7.8.24 |
| ExPASy Enzyme Link: | ExPASy2.7.8.24 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.8.24 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.8.24 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.8.24 |
| IntEnz Enzyme Link: | IntEnz 2.7.8.24 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.8.24 |
| RHEA:14597 | a CDP-1,2-diacyl-sn-glycerol + choline = a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Functional and topological analysis of phosphatidylcholine synthase from Sinorhizobium meliloti. | Solís-Oviedo RL, Martínez-Morales F, Geiger O, Sohlenkamp C | 2012 Apr | 22333179 |
| Expression and physiological relevance of Agrobacterium tumefaciens phosphatidylcholine biosynthesis genes. | Klüsener S, Aktas M, Thormann KM, Wessel M, Narberhaus F | 2009 Jan | 18978052 |
| Phospholipid synthesis in Borrelia burgdorferi: BB0249 and BB0721 encode functional phosphatidylcholine synthase and phosphatidylglycerolphosphate synthase proteins. | Wang XG, Scagliotti JP, Hu LT | 2004 Feb | 14766917 |
| Pathways for phosphatidylcholine biosynthesis in bacteria. | Martínez-Morales F, Schobert M, López-Lara IM, Geiger O | 2003 Dec | 14663079 |
| Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway. | Wilderman PJ, Vasil AI, Martin WE, Murphy RC, Vasil ML | 2002 Sep | 12169604 |
| Cloning and characterization of the gene for phosphatidylcholine synthase. | Sohlenkamp C, de Rudder KE, Rohrs V, Lopez-Lara IM, Geiger O | 2000 Jun 23 | 10858449 |
| Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase. | de Rudder KE, Sohlenkamp C, Geiger O | 1999 Jul 9 | 10391951 |