EC number:2.7.8.41
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.8 Transferases for other substituted phosphate groups |
| ID: | 2.7.8.41 |
|---|---|
| Description: | Cardiolipin synthase (CMP-forming). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.8.41 |
| BRENDA Enzyme Link: | BRENDA 2.7.8.41 |
| KEGG Enzyme Link: | KEGG2.7.8.41 |
| BioCyc Enzyme Link: | BioCyc 2.7.8.41 |
| ExPASy Enzyme Link: | ExPASy2.7.8.41 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.8.41 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.8.41 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.8.41 |
| IntEnz Enzyme Link: | IntEnz 2.7.8.41 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.8.41 |
| RHEA:32931 | 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a CDP-1,2-diacyl-sn-glycerol = a cardiolipin + CMP + H(+) |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cardiolipin synthase from yeast. | Schlame M, Greenberg ML | 1997 Sep 4 | 9370334 |
| Isolation, purification and characterization of Cardiolipin synthase from Mycobacterium phlei {PRIVATE}. | Sarma PV, Srikanth L, Venkatesh K, Murthy PS, Sarma PU | 2013 | 23930021 |
| Biochemical characterization and regulation of cardiolipin synthase in Saccharomyces cerevisiae. | Tamai KT, Greenberg ML | 1990 Sep 18 | 2171667 |
| A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria. | Sandoval-Calderón M, Geiger O, Guan Z, Barona-Gómez F, Sohlenkamp C | 2009 Jun 26 | 19439403 |
| Identification and characterization of human cardiolipin synthase. | Houtkooper RH, Akbari H, van Lenthe H, Kulik W, Wanders RJ, Frentzen M, Vaz FM | 2006 May 29 | 16678169 |
| Solubilization, purification, and characterization of cardiolipin synthase from rat liver mitochondria. Demonstration of its phospholipid requirement. | Schlame M, Hostetler KY | 1991 Nov 25 | 1657995 |
| Cardiolipin synthase of Arabidopsis thaliana. | Nowicki M, Müller F, Frentzen M | 2005 Apr 11 | 15811335 |