EC number:2.7.8.45

Enzyme

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EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.8 Transferases for other substituted phosphate groups
ID:2.7.8.45
Description:Teichoic acid glycerol-phosphate transferase.
Alternative Name: Teichoic acid glycerol-phosphate primase.
Cath: 3.40.50.11820; 3.40.50.12580;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.8.45
BRENDA Enzyme Link: BRENDA 2.7.8.45
KEGG Enzyme Link: KEGG2.7.8.45
BioCyc Enzyme Link: BioCyc 2.7.8.45
ExPASy Enzyme Link: ExPASy2.7.8.45
EC2PDB Enzyme Link: EC2PDB 2.7.8.45
ExplorEnz Enzyme Link: ExplorEnz 2.7.8.45
PRIAM enzyme-specific profiles Link: PRIAM 2.7.8.45
IntEnz Enzyme Link: IntEnz 2.7.8.45
MEDLINE Enzyme Link: MEDLINE 2.7.8.45

EC number:2.7.8.45

MSA:

2.7.8.45;
Phylogenetic Tree:

2.7.8.45;
Uniprot:
M-CSA:
RHEA:50880 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol = 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[O;H0;+0:8]-[*:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Wall teichoic acids of gram-positive bacteria.Brown S, Santa Maria JP Jr, Walker S201324024634
Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways.Brown S, Meredith T, Swoboda J, Walker S2010 Oct 2921035733
A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps.Brown S, Zhang YH, Walker S2008 Jan18215769