EC number:2.7.9.2
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.9 Phosphotransferases with paired acceptors |
| ID: | 2.7.9.2 | ||
|---|---|---|---|
| Description: | Pyruvate, water dikinase. | ||
| Alternative Name: |
Pyruvate,water dikinase. Phosphoenolpyruvate synthase. | ||
| Prosite: | PDOC00527; | ||
| PDB: |
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| Cath: | 1.10.274.10; 3.20.20.60; 3.30.1340.10; 3.30.1490.20; 3.30.450.40; 3.30.470.20; 3.50.30.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.9.2 |
| BRENDA Enzyme Link: | BRENDA 2.7.9.2 |
| KEGG Enzyme Link: | KEGG2.7.9.2 |
| BioCyc Enzyme Link: | BioCyc 2.7.9.2 |
| ExPASy Enzyme Link: | ExPASy2.7.9.2 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.9.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.9.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.9.2 |
| IntEnz Enzyme Link: | IntEnz 2.7.9.2 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.9.2 |
| RHEA:11364 | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[CH3;+0:3])=[O;H0;+0:4].[*:5]-[O;H0;+0:6]-[P;H0;+0:7](=[*:8])(-[*:9])-[O;H0;+0:10]-[P;H0;+0:11](=[*:12])(-[*:13])-[*:14].[OH2;+0:15]>>[*:1]-[C;H0;+0:2](=[CH2;+0:3])-[O;H0;+0:4]-[P;H0;+0:7](=[*:8])(-[*:9])-[OH;+0:10].[*:5]-[OH;+0:6].[*:12]=[P;H0;+0:11](-[*:13])(-[*:14])-[OH;+0:15] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Pyruvate,phosphate dikinase from Bacteroides symbiosus. | Reeves RE | 1971 Nov | 5144757 |
| Phosphoenolpyruvate synthetase of Escherichia coli. Purification, some properties, and the role of divalent metal ions. | Berman KM, Cohn M | 1970 Oct 25 | 4319237 |
| A new enzyme for the interconversion of pyruvate and phosphopyruvate and its role in the C4 dicarboxylic acid pathway of photosynthesis. | Hatch MD, Slack CR | 1968 Jan | 4305612 |
| The pyruvate-phosphate dikinase reaction. The fate of phosphate and the equilibrium. | Reeves RE, Menzies RA, Hsu DS | 1968 Oct 25 | 4302788 |
| A new enzyme with the glycolytic function of pyruvate kinase. | Reeves RE | 1968 Jun 10 | 4297474 |
| The mechanism of the phosphoenolpyruvate synthase reaction. | Cooper RA, Kornberg HL | 1967 Jun 13 | 4293109 |
| Phosphoenolpyruvate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus. | Hutchins AM, Holden JF, Adams MW | 2001 Jan | 11133966 |