| EC Tree |
| 2. Transferases |
| 2.8 Transferring sulfur-containing groups |
| 2.8.1 Sulfurtransferases |
| ID: | 2.8.1.14 |
|---|---|
| Description: | tRNA-5-taurinomethyluridine 2-sulfurtransferase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.8.1.14 |
| BRENDA Enzyme Link: | BRENDA 2.8.1.14 |
| KEGG Enzyme Link: | KEGG2.8.1.14 |
| BioCyc Enzyme Link: | BioCyc 2.8.1.14 |
| ExPASy Enzyme Link: | ExPASy2.8.1.14 |
| EC2PDB Enzyme Link: | EC2PDB 2.8.1.14 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.8.1.14 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.8.1.14 |
| IntEnz Enzyme Link: | IntEnz 2.8.1.14 |
| MEDLINE Enzyme Link: | MEDLINE 2.8.1.14 |
| RHEA:47040 | 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] = 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein] |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[S;H0;+0:8]-[SH;+0:9].[*:10]:[c;H0;+0:11](:[*:12])=[O;H0;+0:13]>>[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:13].[*:7]-[SH;+0:8].[*:10]:[c;H0;+0:11](:[*:12])=[S;H0;+0:9] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Deletion of the MTO2 gene related to tRNA modification causes a failure in mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae. | Wang X, Yan Q, Guan MX | 2007 Sep 4 | 17706197 |
| Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. | Umeda N, Suzuki T, Yukawa M, Ohya Y, Shindo H, Watanabe K, Suzuki T | 2005 Jan 14 | 15509579 |