EC number:2.8.1.2
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.8 Transferring sulfur-containing groups |
| 2.8.1 Sulfurtransferases |
| ID: | 2.8.1.2 | ||
|---|---|---|---|
| Description: | 3-mercaptopyruvate sulfurtransferase. | ||
| Prosite: | PDOC00322; | ||
| PDB: |
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| Cath: | 3.30.1670.10; 3.40.250.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.8.1.2 |
| BRENDA Enzyme Link: | BRENDA 2.8.1.2 |
| KEGG Enzyme Link: | KEGG2.8.1.2 |
| BioCyc Enzyme Link: | BioCyc 2.8.1.2 |
| ExPASy Enzyme Link: | ExPASy2.8.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 2.8.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.8.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.8.1.2 |
| IntEnz Enzyme Link: | IntEnz 2.8.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 2.8.1.2 |
| RHEA:21740 | 3-mercaptopyruvate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate |
| RULE(radius=1) | [*:1]#[CH;+0:2].[*:3]-[CH2;+0:4]-[SH;+0:5]>>[*:1]#[C;H0;+0:2]-[SH;+0:5].[*:3]-[CH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A study of the cooper content of beta-mercaptopyruvate trans-sulfurase. | Van den Hamer CJ, Morell AG, Scheinberg IH | 1967 May 25 | 6026243 |
| Purification and properties of mercaptopyruvate sulfur transferase of Escherichia coli. | Vachek H, Wood JL | 1972 Jan 20 | 4550801 |
| Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide. | Mikami Y, Shibuya N, Kimura Y, Nagahara N, Ogasawara Y, Kimura H | 2011 Nov 1 | 21732914 |
| 3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain. | Shibuya N, Tanaka M, Yoshida M, Ogasawara Y, Togawa T, Ishii K, Kimura H | 2009 Apr | 18855522 |
| Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis. | Nagahara N, Katayama A | 2005 Oct 14 | 16107337 |
| Enzymatic formation of polysulfides from mercaptopyruvate. | HYLIN JW, WOOD JL | 1959 Aug | 13673028 |
| Enzymic transfer of sulfur from mercaptopyruvate to sulfate or sulfinates. | SORBO B | 1957 May | 13436433 |
| Specificity studies on the beta-mercaptopyruvate-cyanide transsulfuration system. | FIEDLER H, WOOD JL | 1956 Sep | 13367011 |