EC number:2.8.2.11
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.8 Transferring sulfur-containing groups |
| 2.8.2 Sulfotransferases |
| ID: | 2.8.2.11 |
|---|---|
| Description: | Galactosylceramide sulfotransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.8.2.11 |
| BRENDA Enzyme Link: | BRENDA 2.8.2.11 |
| KEGG Enzyme Link: | KEGG2.8.2.11 |
| BioCyc Enzyme Link: | BioCyc 2.8.2.11 |
| ExPASy Enzyme Link: | ExPASy2.8.2.11 |
| EC2PDB Enzyme Link: | EC2PDB 2.8.2.11 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.8.2.11 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.8.2.11 |
| IntEnz Enzyme Link: | IntEnz 2.8.2.11 |
| MEDLINE Enzyme Link: | MEDLINE 2.8.2.11 |
| RHEA:41744 | 3'-phosphoadenylyl sulfate + a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol = a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[S;H0;+0:3](=[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[S;H0;+0:3](=[*:5])(-[*:6])-[O;H0;+0:8]-[*:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells. | Honke K, Yamane M, Ishii A, Kobayashi T, Makita A | 1996 Mar | 8830034 |
| RHEA:20613 | 3'-phosphoadenylyl sulfate + an N-acyl-beta-D-galactosyl-sphing-4-enine = adenosine 3',5'-bisphosphate + H(+) + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[S;H0;+0:3](=[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[S;H0;+0:3](=[*:5])(-[*:6])-[O;H0;+0:8]-[*:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells. | Honke K, Yamane M, Ishii A, Kobayashi T, Makita A | 1996 Mar | 8830034 |
| Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides. | McKhann GM, Levy R, Ho W | 1965 Jul 12 | 5850675 |
| Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma. | Sakakibara N, Gasa S, Kamio K, Makita A, Koyanagi T | 1989 Jan 15 | 2562926 |