Enzyme

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     2. Transferases
        2.8 Transferring sulfur-containing groups
            2.8.2 Sulfotransferases
ID:2.8.2.5
Description:Chondroitin 4-sulfotransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.8.2.5
BRENDA Enzyme Link: BRENDA 2.8.2.5
KEGG Enzyme Link: KEGG2.8.2.5
BioCyc Enzyme Link: BioCyc 2.8.2.5
ExPASy Enzyme Link: ExPASy2.8.2.5
EC2PDB Enzyme Link: EC2PDB 2.8.2.5
ExplorEnz Enzyme Link: ExplorEnz 2.8.2.5
PRIAM enzyme-specific profiles Link: PRIAM 2.8.2.5
IntEnz Enzyme Link: IntEnz 2.8.2.5
MEDLINE Enzyme Link: MEDLINE 2.8.2.5
MSA:

2.8.2.5;

Phylogenetic Tree:

2.8.2.5;

Uniprot:
M-CSA:
RHEA:16101 n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate = n adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate + n H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[S;H0;+0:3](=[*:4])(=[*:5])-[*:6].[*:7]-[OH;+0:8]>>[*:1]-[OH;+0:2].[*:4]=[S;H0;+0:3](=[*:5])(-[*:6])-[O;H0;+0:8]-[*:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases.Kang HG, Evers MR, Xia G, Baenziger JU, Schachner M2002 Sep 2012080076
Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase.Okuda T, Mita S, Yamauchi S, Matsubara T, Yagi F, Yamamori D, Fukuta M, Kuroiwa A, Matsuda Y, Habuchi O2000 Nov11056388
Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M2000 Jun 3010781601
Molecular cloning and expression of chondroitin 4-sulfotransferase.Yamauchi S, Mita S, Matsubara T, Fukuta M, Habuchi H, Kimata K, Habuchi O2000 Mar 2410722746