EC number:2.8.3.13
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.8 Transferring sulfur-containing groups |
| 2.8.3 CoA-transferases |
| ID: | 2.8.3.13 |
|---|---|
| Description: | Succinate--hydroxymethylglutarate CoA-transferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.8.3.13 |
| BRENDA Enzyme Link: | BRENDA 2.8.3.13 |
| KEGG Enzyme Link: | KEGG2.8.3.13 |
| BioCyc Enzyme Link: | BioCyc 2.8.3.13 |
| ExPASy Enzyme Link: | ExPASy2.8.3.13 |
| EC2PDB Enzyme Link: | EC2PDB 2.8.3.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.8.3.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.8.3.13 |
| IntEnz Enzyme Link: | IntEnz 2.8.3.13 |
| MEDLINE Enzyme Link: | MEDLINE 2.8.3.13 |
| RHEA:24948 | 3-hydroxy-3-methylglutarate + malonyl-CoA = (3S)-hydroxy-3-methylglutaryl-CoA + malonate |
| RULE(radius=1) | [C:1][S:2][C:3](=[O:4])[C:5].[O:10][C:11](=[O:12])[C:13]>>[O:10][C:3](=[O:4])[C:5].[C:1][S:2][C:11](=[O:12])[C:13] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver. | Deana R, Rigoni F, Deana AD, Galzigna L | 1981 Nov 13 | 6946836 |
| RHEA:12284 | 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-hydroxy-3-methylglutaryl-CoA + succinate |
| RULE(radius=1) | [C:1][S:2][C:3](=[O:4])[C:5].[O:10][C:11](=[O:12])[C:13]>>[O:10][C:3](=[O:4])[C:5].[C:1][S:2][C:11](=[O:12])[C:13] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver. | Deana R, Rigoni F, Deana AD, Galzigna L | 1981 Nov 13 | 6946836 |
| C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, the enzyme that converts glutarate to glutaryl-CoA. | Marlaire S, Van Schaftingen E, Veiga-da-Cunha M | 2014 Jan | 23893049 |