Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.13
Description:Sterol esterase.
Alternative Name: Triterpenol esterase.
Cholesterol esterase.
Cholesterol ester synthase.
Prosite: PDOC00112;
PDB:
PDBScop
Cath: 3.40.50.1820;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.13
BRENDA Enzyme Link: BRENDA 3.1.1.13
KEGG Enzyme Link: KEGG3.1.1.13
BioCyc Enzyme Link: BioCyc 3.1.1.13
ExPASy Enzyme Link: ExPASy3.1.1.13
EC2PDB Enzyme Link: EC2PDB 3.1.1.13
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.13
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.13
IntEnz Enzyme Link: IntEnz 3.1.1.13
MEDLINE Enzyme Link: MEDLINE 3.1.1.13
MSA:

3.1.1.13;

Phylogenetic Tree:

3.1.1.13;

Uniprot:
M-CSA:
RHEA:36403 a cholesterol ester + H2O = a fatty acid + cholesterol + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

RHEA:10100 a steryl ester + H2O = a fatty acid + a sterol + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Lipoamidase activity in normal and mutagenized pancreatic cholesterol esterase (bile salt-stimulated lipase).Hui DY, Hayakawa K, Oizumi J1993 Apr 18471055
Purification and properties of pancreatic juice cholesterol esterase.Hyun J, Kothari H, Herm E, Mortenson J, Treadwell CR, Vahouny GV1969 Apr 105780846
Enzymatic synthesis and hydrolysis of cholesterol esters.Vahouny GV, Treadwell CR19684877146
Studies on sterol-ester hydrolase from Fusarium oxysporum. I. Partial purification and properties.Okawa Y, Yamaguchi T1977 May19426