| ID: | 3.1.1.17 |
|---|---|
| Description: | Gluconolactonase. |
| Alternative Name: |
Lactonase. Aldonolactonase. |
| Cath: | 2.120.10.30; 3.40.50.1360; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 3.1.1.17 |
| BRENDA Enzyme Link: | BRENDA 3.1.1.17 |
| KEGG Enzyme Link: | KEGG3.1.1.17 |
| BioCyc Enzyme Link: | BioCyc 3.1.1.17 |
| ExPASy Enzyme Link: | ExPASy3.1.1.17 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.1.17 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.1.17 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.1.17 |
| IntEnz Enzyme Link: | IntEnz 3.1.1.17 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.1.17 |
| RHEA:10440 | D-glucono-1,5-lactone + H2O = D-gluconate + H(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>([*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]) |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel carbohydrate:acceptor oxidoreductase from Microdochium nivale. | Xu F, Golightly EJ, Fuglsang CC, Schneider P, Duke KR, Lam L, Christensen S, Brown KM, Jørgensen CT, Brown SH | 2001 Feb | 11179980 |
| Structural basis of the γ-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase. | Aizawa S, Senda M, Harada A, Maruyama N, Ishida T, Aigaki T, Ishigami A, Senda T | 2013 | 23349732 |
| Crystal structure of human senescence marker protein 30: insights linking structural, enzymatic, and physiological functions . | Chakraborti S, Bahnson BJ | 2010 Apr 27 | 20329768 |
| Senescence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy. | Kondo Y, Inai Y, Sato Y, Handa S, Kubo S, Shimokado K, Goto S, Nishikimi M, Maruyama N, Ishigami A | 2006 Apr 11 | 16585534 |
| Coimmobilization of gluconolactonase with glucose oxidase for improvement in kinetic property of enzymatically induced volume collapse in ionic gels. | Ogawa K, Nakajima-Kambe T, Nakahara T, Kokufuta E | 2002 May-Jun | 12005536 |