EC number:3.1.1.53
| ID: | 3.1.1.53 |
|---|---|
| Description: | Sialate O-acetylesterase. |
| Cath: | 3.90.20.10; 2.20.70.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.1.53 |
| BRENDA Enzyme Link: | BRENDA 3.1.1.53 |
| KEGG Enzyme Link: | KEGG3.1.1.53 |
| BioCyc Enzyme Link: | BioCyc 3.1.1.53 |
| ExPASy Enzyme Link: | ExPASy3.1.1.53 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.1.53 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.1.53 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.1.53 |
| IntEnz Enzyme Link: | IntEnz 3.1.1.53 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.1.53 |
| RHEA:25564 | H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].[OH2;+0:6]>>[*:1]-[OH;+0:2].[*:4]=[C;H0;+0:3](-[*:5])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture. | Langereis MA, Zeng Q, Heesters BA, Huizinga EG, de Groot RJ | 2012 Jan | 22291594 |
| Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds. | Garcia-Sastre A, Villar E, Manuguerra JC, Hannoun C, Cabezas JA | 1991 Jan 15 | 1991039 |
| Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases. | Langereis MA, Zeng Q, Gerwig GJ, Frey B, von Itzstein M, Kamerling JP, de Groot RJ, Huizinga EG | 2009 Sep 15 | 19721004 |
| Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution. | Zeng Q, Langereis MA, van Vliet AL, Huizinga EG, de Groot RJ | 2008 Jul 1 | 18550812 |
| RHEA:22600 | H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].[OH2;+0:6]>>[*:1]-[OH;+0:2].[*:4]=[C;H0;+0:3](-[*:5])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture. | Langereis MA, Zeng Q, Heesters BA, Huizinga EG, de Groot RJ | 2012 Jan | 22291594 |
| Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds. | Garcia-Sastre A, Villar E, Manuguerra JC, Hannoun C, Cabezas JA | 1991 Jan 15 | 1991039 |
| Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases. | Langereis MA, Zeng Q, Gerwig GJ, Frey B, von Itzstein M, Kamerling JP, de Groot RJ, Huizinga EG | 2009 Sep 15 | 19721004 |
| Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution. | Zeng Q, Langereis MA, van Vliet AL, Huizinga EG, de Groot RJ | 2008 Jul 1 | 18550812 |