Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.55
Description:Acetylsalicylate deacetylase.
Alternative Name: Aspirin esterase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.55
BRENDA Enzyme Link: BRENDA 3.1.1.55
KEGG Enzyme Link: KEGG3.1.1.55
BioCyc Enzyme Link: BioCyc 3.1.1.55
ExPASy Enzyme Link: ExPASy3.1.1.55
EC2PDB Enzyme Link: EC2PDB 3.1.1.55
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.55
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.55
IntEnz Enzyme Link: IntEnz 3.1.1.55
MEDLINE Enzyme Link: MEDLINE 3.1.1.55
MSA:

3.1.1.55;

Phylogenetic Tree:

3.1.1.55;

Uniprot:
M-CSA:
RHEA:11752 acetylsalicylate + H2O = acetate + H(+) + salicylate
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:5]-[OH;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mammalian tissue acetylsalicylic acid esterase(s): identification, distribution and discrimination from other esterases.Ali B, Kaur S1983 Aug6875867
Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver.White KN, Hope DB1984 Mar 296704404
Aspirin hydrolyzing esterases from rat liver cytosol.Kim DH, Yang YS, Jakoby WB1990 Aug 12383281